Human breathing modeling through nose and mouth

Computational modeling of human respiratory airflow dynamics

Background

• Project: Biomedical engineering research collaboration for respiratory health applications
• Understanding airflow patterns in human respiratory system is crucial for medical device design, drug delivery optimization, and respiratory disease treatment.
• Key physics concepts: turbulent flows, heat and mass transfer, particle transport, biological fluid dynamics, aerosol deposition.

Issues

• Accurate modeling of complex nasal cavity geometry and airflow patterns during breathing cycles.
• Investigation of particle deposition patterns for pharmaceutical aerosol delivery optimization.
• Analysis of airflow differences between nasal and oral breathing pathways.
• Assessment of respiratory disease effects on airflow dynamics and particle transport.
• Development of patient-specific models for personalized medical treatments.

Contributions to the project

• Development of high-fidelity computational models of human nasal and oral cavities.
• Implementation of large-eddy simulation (LES) for accurate turbulence modeling in respiratory flows.
• Lagrangian particle tracking for aerosol deposition analysis in respiratory system.
• Investigation of breathing cycle effects on airflow patterns and heat/mass transfer.
• Validation studies comparing computational results with experimental measurements.
• Analysis of pathological conditions impact on respiratory airflow dynamics.

Technical environment

• Computing: Linux HPC cluster, MPI, PETSc
• Programming: Python, C/C++
• CFD Software: VFS Geophysics
• Meshing: Pointwise, Blender for complex anatomical geometries
• Visualization: ParaView, Tecplot
• Data Analysis: Python scientific libraries, statistical analysis tools

Related Publications

• High-fidelity computational fluid dynamics study of respiratory airflow patterns (2024)
• Biomedical engineering research for respiratory health applications (2023)

This research contributes to improving respiratory health treatments and medical device design through detailed understanding of human breathing dynamics.